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Drug & Alcohol Rehab Centers in Knoxville, Tennessee

Discover 16 addiction treatment facilities in Knoxville. Our comprehensive directory helps you find the right rehabilitation center with 24/7 support available, licensed facilities, and insurance accepted at most locations. Whether you need detox services, residential treatment, outpatient programs, or sober living arrangements, find the perfect match for your recovery journey.

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Showing 16 of 16 results

Cedar Recovery
+9 photos
Cedar Recovery

South Knoxville

2805 West Governor John Sevier Highway, 37920
865-298-3558
Cedar Recovery in Knoxville, TN provides comprehensive substance use treatment with both outpatient and residential care options. Specializing in evidence-based therapies including cognitive behavioral therapy, trauma counseling, and anger management, the facility also offers medication-assisted treatment with methadone, buprenorphine, and naltrexone. As a DEA-registered and SAMHSA-certified opioid treatment program, Cedar Recovery delivers clinically rigorous care supported by multiple healthcare accreditations.
Substance use treatment
Cedar Recovery
+9 photos
Cedar Recovery

East Knoxville

8712 Asheville Highway, 37924
865-932-3633
Cedar Recovery in Knoxville, Tennessee provides comprehensive substance use treatment through multiple evidence-based approaches tailored to individual recovery needs. Specializing in outpatient care including medication-assisted treatment with methadone, buprenorphine, and naltrexone, the facility combines therapeutic modalities such as cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling. CARF-accredited Cedar Recovery stands out for integrating telehealth options, making recovery support accessible while maintaining personalized clinical oversight.
Substance use treatment
Cherokee Health Systems
+9 photos
2018 Western Avenue, 37921
865-544-0406
Cherokee Health Systems in Knoxville, TN is a Federally Qualified Health Center specializing in integrated treatment for substance use disorders and co-occurring mental health conditions. They offer evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed care through both in-person intensive outpatient and telemedicine options. Their medication-assisted treatment programs with methadone, buprenorphine, and naltrexone provide comprehensive pathways to recovery for adults and children.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Crossroads Treatment Centers
+9 photos
7039 Maynardville Pike, 37918
800-805-6989
Crossroads Treatment Centers in Knoxville, TN specializes in comprehensive substance use disorder treatment with a particular focus on supporting pregnant and postpartum women. The center offers evidence-based outpatient services including medication-assisted treatment (methadone, buprenorphine, and naltrexone), individualized counseling, and relapse prevention strategies delivered both in-person and via secure telehealth. As a DEA-registered and state-accredited facility, Crossroads combines medical oversight with compassionate care tailored to the unique needs of women navigating recovery during pregnancy and early motherhood.
Substance use treatment
Knox Area Rescue Ministries
+9 photos
Knox Area Rescue Ministries

Serenity Ministries

- - -, 37917
865-673-6551
Knox Area Rescue Ministries in Knoxville, TN provides comprehensive long-term residential treatment for women struggling with substance use disorders. The facility combines evidence-based therapies including 12-step facilitation, motivational interviewing, and trauma-focused counseling with stable transitional housing in a supportive community setting. Specialized programming addresses anger management and relapse prevention to support lasting recovery and successful reintegration.
Substance use treatmentTransitional housing, halfway house, or sober home
A DUI and Defensive Driving School Inc
+7 photos
111 Center Park Drive, 37922
865-335-5286
A DUI and Defensive Driving School Inc in Knoxville, TN specializes in substance use treatment with a focus on cognitive behavioral therapy for individuals involved in the criminal justice system. Serving adolescents, adult women, and young adults through accessible outpatient programs, this facility combines evidence-based addiction treatment with driving education. Accredited by multiple state agencies and the Council on Accreditation, they provide comprehensive support for recovery and rehabilitation.
Substance use treatment
Cumberland Heights
+5 photos
Cumberland Heights

Outpt Serv of Knoxville/Papermill

1320 Papermill Pointe Way, 37909
865-213-9003
Cumberland Heights in Knoxville, TN is a Joint Commission-accredited substance use treatment facility offering comprehensive outpatient and intensive outpatient programs. The center specializes in evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling, with flexible telemedicine options for accessibility. Their integrated approach addresses both addiction and underlying behavioral health concerns to support lasting recovery.
Substance use treatment
Health Connect America
+5 photos
5743 Western Avenue, 37921
865-247-7045
Health Connect America in Knoxville, TN specializes in integrated treatment for substance use disorders and co-occurring mental health conditions in both adults and adolescents. Their evidence-based approach combines cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling through flexible outpatient and intensive outpatient settings, including telehealth options. Accredited by the Council on Accreditation and state agencies, they serve individuals involved in the criminal justice system and those managing complex dual diagnoses.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Helen Ross McNabb Center
+5 photos
201 West Springdale Avenue, 37917
865-637-9711
Helen Ross McNabb Center in Knoxville, TN is a comprehensive substance use and mental health treatment facility specializing in integrated care for adults and seniors with co-occurring disorders. The center offers flexible treatment levels from intensive outpatient programs to medication-assisted therapy, including methadone and buprenorphine services. Accredited by CARF and state agencies, it combines evidence-based therapies like cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling with telehealth options for accessible care.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Helen Ross McNabb Center
+5 photos
Helen Ross McNabb Center

Knox County Adult Center

205 West Springdale Avenue, 37917
865-637-9711
Helen Ross McNabb Center in Knoxville, TN specializes in integrated treatment for substance use disorders and co-occurring mental health conditions in adults and children. The center employs evidence-based approaches including motivational interviewing, trauma-focused counseling, and relapse prevention through both intensive outpatient and standard outpatient settings. Accredited by CARF and state agencies, they serve diverse populations including survivors of sexual abuse, individuals with HIV/AIDS, and those managing complex dual diagnoses.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Cherokee Health Systems
+3 photos
2202 Martin Luther King Jr Avenue, 37915
865-522-6097
Cherokee Health Systems in Knoxville, TN provides comprehensive substance use treatment and co-occurring mental health services for adults and children through evidence-based outpatient programs. As a Federally Qualified Health Center, they offer medication-assisted treatment with methadone, buprenorphine, and naltrexone alongside therapy modalities including cognitive behavioral therapy, motivational interviewing, and trauma-informed care. Their integrated approach addresses the complex relationship between addiction and serious mental illness or emotional disturbance.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
BHG Knoxville Citico Treatment Center
+2 photos
412 Citico Street, 37921
865-522-0661
BHG Knoxville Citico Treatment Center in Knoxville, Tennessee provides comprehensive substance use disorder treatment, including medical detoxification and medication-assisted therapies for opioid addiction. The center specializes in evidence-based approaches such as cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling delivered through flexible outpatient and intensive outpatient formats. With DEA and SAMHSA certifications, including opioid treatment program status, BHG Citico combines clinical expertise with accessible care options including telemedicine services.
DetoxificationSubstance use treatment
BHG Knoxville Bernard Treatment Center
+1 photos
626 Bernard Avenue, 37921
865-522-0161
BHG Knoxville Bernard Treatment Center in Knoxville, TN specializes in comprehensive substance use disorder treatment with outpatient detoxification and medication-assisted treatment options including methadone and buprenorphine. The center employs evidence-based therapies such as cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling, alongside convenient telemedicine services for ongoing recovery support. Fully accredited by The Joint Commission and SAMHSA as a certified opioid treatment program, the facility delivers professional, compassionate care tailored to individual recovery needs.
DetoxificationSubstance use treatment
Helen Ross McNabb Center
+1 photos
5310 Ball Camp Pike, 37921
865-523-4704 x0
Helen Ross McNabb Center in Knoxville, TN provides comprehensive detoxification and substance use treatment with specialized care for co-occurring mental health conditions. The facility offers residential and 24-hour treatment programs utilizing evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling. Accredited by CARF and state agencies, it serves adults and trauma survivors with integrated mental health and addiction recovery support.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Cherokee Health Systems - Placeholder
538 West 5th Avenue, 37917
865-525-2104
Cherokee Health Systems in Knoxville, TN is a Federally Qualified Health Center specializing in integrated substance use and mental health treatment for adults and children. The facility offers comprehensive outpatient care including medication-assisted treatment with methadone, buprenorphine, and naltrexone, alongside evidence-based therapies like cognitive behavioral therapy, motivational interviewing, and trauma counseling. They uniquely address co-occurring pain and substance use disorders with a holistic, evidence-informed approach.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
EM Jellinek Center - Placeholder
130 Hinton Avenue, 37917
865-525-4627
EM Jellinek Center in Knoxville, TN provides comprehensive substance use treatment through residential and transitional housing programs designed for diverse populations including veterans, seniors, and individuals with co-occurring disorders. The center combines evidence-based therapies like cognitive behavioral therapy, motivational interviewing, and 12-step facilitation to address complex needs including pain management and mental health conditions. As a state-accredited facility, EM Jellinek offers short-term and long-term residential care tailored to each client's recovery journey.
Substance use treatmentTransitional housing, halfway house, or sober home

Addiction Treatment in Knoxville

Knoxville is home to a diverse range of addiction treatment facilities, offering comprehensive care for individuals struggling with substance abuse and co-occurring mental health disorders. Whether you're a resident of Knoxville or traveling for treatment, you'll find quality rehabilitation centers that can help you begin your recovery journey.

Why Choose Treatment in Knoxville?

  • • Accessibility: Multiple treatment centers throughout the city with various specializations
  • • Quality Care: Licensed and accredited facilities with experienced professionals
  • • Diverse Options: From luxury rehabs to affordable state-funded programs
  • • Support Network: Strong recovery community with numerous support groups
  • • Continuum of Care: Full spectrum from detox to aftercare services

Types of Programs Available

Treatment centers in Knoxville offer various levels of care to meet different needs:

  • • Medical Detox: Safe, supervised withdrawal management
  • • Inpatient/Residential: 24/7 care in a structured environment
  • • Partial Hospitalization (PHP): Intensive day treatment programs
  • • Intensive Outpatient (IOP): Flexible scheduling for working professionals
  • • Standard Outpatient: Weekly therapy and support groups
  • • Sober Living: Transitional housing for ongoing recovery support

Getting Started with Treatment

Finding the right treatment center in Knoxville starts with understanding your specific needs. Consider factors such as the type of substance use, any co-occurring mental health conditions, insurance coverage, and personal preferences for treatment approach. Many facilities offer free consultations to help you determine the right fit for your recovery journey.